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. Author manuscript; available in PMC: 2018 Jul 28.
Published in final edited form as: J Health Commun. 2016 Jul 28;21(9):989–1005. doi: 10.1080/10810730.2016.1184358

Table 3.

Population/sample characteristics, cancer information seeking behaviors, and cancer-related health outcomes

First Author
  (Year)
Population/
Subpopulation
(Sample Size)
Sample Characteristics Cancer Information
Seeking Behavioral &
Psychosocial Factors
Cancer-Related Health
Outcomes & Theoretical
Frameworks
Cancer
Type
HINTS
(Year)
Hay (2015) Participants
18+ years old
who
completed the
colorectal
cancer mental
module
(1,789/1,937)
148=missing
data
Race/ethnicity:
  7.8% Hispanic
  11.6% Foreign born
  20.3 ± 1.58 years in USa
SES:
  57.3% Some college+
  24.9% ≤$29K
Cancer History:
  10.3% family history of
  colorectal cancer
Lower cancer/health
information seeking summary
score was positively associated
with ambiguity about CRC risk
perceptions.

Self-efficacy (n.s).
7.5% did not know their
comparative CRC risk

8.7% did not know their
absolute CRC risk
CRC HINTS 2
(2005)
Chen (2014) 55+ year old
adults
(1,818)
Race/ethnicity:
  78% White
  10% Hispanic
SES:
  56% Some college+
  58% ≤$35K
Cancer History:
  66% family history of
  cancer
Online cancer information
seeking was positively
associated with CRC screening
adherence.

Seeking experiences (n.s.)
Self-efficacy (n.s.)
64% were compliant based on
the following CRC screening
guidelines:
  • Colonoscopy <10 years

  • Sigmoidoscopy <5 years

  • FOBT <2 years

Precede-Proceed Model
CRC HINTS 1
(2003)
Madadi (2014) Adherent and
non-adherent
women
>40 years old
(2,370)
Race/ethnicity:
  77% White
SES:
  56% Some college+
  36% ≤$25,000/year
  49% Employed
Cancer History:
  75% Family member
  had cancer
The association between cancer
information seeking and
mammography
attitudes/screening adherence
was not statistically significant.
70% adherent
  • 73% of women 40–64 years were adherent

  • 65% of women 65+ years old were adherent

56% of non-adherent women
were thinking about getting a
mammogram
Breast
cancer
HINTS 1
(2003)
Kontos (2012) Online and
offline cancer
information
seekers &
non-seekers
(7,674)
Race/ethnicity:
  65% NH White
  12% Hispanic
SES:
  60% Some college+
  30% <$35,000/year
Cancer History:
  Not reported
Online cancer information
seeking was positively
associated with HPV vaccine
awareness and knowledge,
which was significantly higher
compared to non-seekers.

Offline vs. online (n.s.)
70% heard of HPV vaccine
70% HPV was a STI
75% HPV cause cervical cancer
(Note: Awareness/knowledge
highest among online seekers)

Structural Influence Model of
Communication Inequalities
Cervical
cancer
HINTS 3
(2007)
Ortiz (2011) Puerto Rican
adults
(611)
Race/ethnicity:
  Not reported SES:
  44.5% College+d
  40.2% Employed
Cancer History:
  Not reported
Cancer information seekers
were more aware of genetic
testing than non-seekers.
55.8% had heard of direct-to-
consumer genetic tests

4.3% reported ever having a
genetic test.
Genetic
Testing
HINTS PR
(2009)
Kealey (2010) US adults
(5,586)
Race/ethnicity:
  76.9% White
  9.3% Hispanic
SES:
  60.3% Some college+
  40.7% <$35,000/year
Cancer History:
  Not reported
Cancer information seekers
experienced significantly less
cancer information overload
than non-seekers.

Cancer information seeking was
not significantly associated with
cancer beliefs or risk
perceptions.
Cancer information overload
(i.e., ambiguity about how to
prevent cancer), beliefs about
behavioral/lifestyle cancer risk
factors, and perceptions of
comparative risk of getting
cancer were assessed.
All
cancers
HINTS 2
(2005)
Zhao (2010) US adults
(5,586)
Race/ethnicity:
  69.9% White
  13.0% Hispanic
SES:
  55.6% College+d
  58.6% Employed
Cancer History:
  11.4% Had cancer
Cancer information
seeking/self-efficacy was
inversely associated with
having undesirable beliefs about
cancer among Whites only.

Surrogate seeking (n.s.)
Undesirable cancer beliefs were
compared between US and
foreign born Whites and
Hispanics:
  • Cannot lower risk

  • Too many recommendations

  • Everything causes cancer

  • Reluctant to get checked

All
cancers
HINTS 2
(2005)
Finney-Rutten (2009) Smokers
(2,257)
Sociodemographics:
  59.7% NH White
  13.9% Hispanic
SES:
  41.8% College+
  38.9% <$25,000/year
Cancer History:
  11.4% Had cancer
The relationship between online
cancer/health information
seeking and smoking status was
not statistically significant.
Cancer communication
outcomes were assessed among
moderate-heavy, light, and
intermittent tobacco users.
Lung
cancer
(smoking
is also a
risk factor
for other
types of
cancer)
HINTS 1
(2003) &
HINTS 2
(2005)
Han (2009) CRC
(n=1,788),
skin
(n=1,594),
and lung
(n=1,777)
cancer mental
modules
participants
(5,159)
Race/ethnicity:
  79.9% White
SES:
  51.7% College+
Cancer History:
  Not reported
Cancer information seeking was
inversely associated with
ambiguity about CRC
prevention.

Skin cancer (n.s.)
Lung cancer (n.s.)
Ambiguity about CRC, skin, and
lung cancer prevention was
assessed.
CRC,
skin, and
lung
cancer
HINTS 2
(2005)
Hay (2009) Skin cancer
mental
module
participants
(1,633)
Race/ethnicity:
  66.9% NH White
  14.7% Hispanic
SES:
  52.6% College+
Cancer History:
  9.9% Family member
  had skin cancer
    5.1% Melanoma
    4.8% Non-melanoma
Skin cancer information
seeking was a positively
associated with some protective
behaviors (i.e., using sunscreen,
wearing sun-protective
clothing).

Skin cancer knowledge (n.s.)
Skin cancer beliefs (n.s.)
Staying in the shade (n.s.)
Skin cancer knowledge, beliefs,
and protective behaviors were
assessed.

Protective behaviors were:
  • Sunscreen use

  • Staying in the shad

  • Use of sun-protective clothing

Skin
cancer
HINTS 2
(2005)
Kaphingst (2009) US adults
(n=5,813)
Race/ethnicity:
  75% NH White
SES:
  60% <$50,000/year
Cancer history:
  13% Had cancer
  65% Family member
   had cancer
Positive beliefs about the
relationship between knowing
one’s family history/genes and
cancer risk reduction was
positively association with
cancer information seeking.
N/A – Cancer information
seeking was the outcome of
interest
All
cancers
HINTS 1
(2003)
Zhao (2009) Smokers who
completed the
lung cancer
mental
module
(n=340)
Race/ethnicity:
  Race/Ethnicity
SES:
  Education
Cancer history:
  Not reported
(Descriptive statistics
were not reported)
Cancer information seeking was
positively associated with
absolute risk, the interaction of
absolute* comparative risk,
response self-efficacy about
lung cancer, and self-efficacy.

Comparative risk (n.s.)
Lung cancer risk perceptions
and response efficacy (i.e., not
much one can do to lower their
lung cancer risk) were assessed.

Risk Perception Attitude
(RPA) Framework
Lung
cancer
(smoking
is also a
risk factor
for other
cancers)
HINTS 2
(2005)
McQueen (2008) 50+ year old
adults
(2,519)
Race/ethnicity:
  74.5% NH White
  6.7% Hispanic
SES:
  Not reported
Cancer History:
  Not reported
Cancer information seeking
(including surrogate seeking)
was not significantly associated
with cancer beliefs (i.e., worry,
risk perceptions).
Cancer worry and risk
perceptions were assessed.
Breast,
CRC,
prostate
cancer
HINTS 1
(2003)
Niederdeppe 2008 US adults
(n=5,585)
Race/ethnicity:
  Race/ethnicity were not
  reported
SES:
  57.5% Some college+
Cancer History:
  11.3% Had cancer
  71.5% Family member
  had cancer
Health knowledge was
positively associated with
cancer information seeking.

Interactions between cancer
news events and education,
health knowledge, and social
networks were also positively
associated with cancer
information seeking.
N/A – Cancer information
seeking was the outcome of
interest

Knowledge Gap Theory
Breast and
lung
cancer,
Hodgkin’s
lymphoma
HINTS 2
(2005)
Shim (2008) Online adults
(3,982)
Race/ethnicity:
  76% NH White
  8% Hispanic
SES:
  75% Some college+
Cancer History:
  10% Had cancer
  65% Family member
  had cancer
Online cancer information
seeking was positively
associated with cancer
knowledge.
Cancer knowledge about
preventive behaviors/lifestyle
factors and screening was
assessed.

Knowledge Gap Theory
All
cancers
HINTS 1
(2003)
Arora (2007) Cancer
information
seekers,
surrogate
seekers, and
non-seekers
(6,369)
Race/ethnicity:
  71.8% NH White
  11.7% Hispanic
SES:
  51.1% Some college+
  59.8% Employed
Cancer History:
  10.9% Had cancer
  54.2% Family member
  had cancer
Cancer information seeking
experiences were positively
associated with cancer beliefs.
Cancer information seeking
experiences and the following
cancer beliefs were examined:
  • Almost everything causes cancer

  • Not much can be done to prevent cancer

  • There are too many recommendations for preventing cancer

All
cancers
HINTS 1
(2003)
Kim (2007) US adults
(n=6,369)
Race/ethnicity:
  76.2% NH White
  7.3% Hispanic
SES:
  29.9% Some college
  24.7% <$25,000
  60.7% Employed
Cancer history:
  5.3% had cancer
  44.3% Family member
  had cancer

Descriptive statistics
reported for overloaded
Health literacy was inversely
associated with cancer
information overload. However,
seekers who were concerned
about the quality of the
information they found were
more likely to feel overloaded.
N/A – Cancer information
overload was the outcome of
interest

National Center for Research
on Evaluation Standards and
Student Testing Model of
Problem Solving

National Trends Survey
Framework

Precaution Adoption Process
Model
All
cancers
HINTS 1
(2003)
Cerully (2006) US adults who
reported
consuming <5
servings of
fruits and
vegetables
daily (5,265)
Descriptive statistics were
not reported
Nonlisters (i.e., did not list F/V
consumption for self or others)
were unexpectedly more likely
to be seekers, but less likely to
trust sources of cancer
information as expected.
Cancer communication,
knowledge, and beliefs were
examined among adults who
consumed less than five servings
of fruits and vegetables daily.
All
cancers
HINTS 1
(2003)
Ford (2006) 45+ year old
adults
(3,131)
Race/ethnicity:
  77.9% NH White
  7.6% Hispanic
SES:
  47.6% Some college
  31.2% <$25,000
Cancer history:
  16.7% had cancer
  67.3% Family member
  had cancer
Non-seekers were less
knowledgeable about CRC
screening
Knowledge of CRC screening
recommendations was examined
CRC HINTS 1
(2003)
Ling (2006) >50 years old
adults
(2,670)
Race/ethnicity:
  80.0% White
  Hispanic not reported
SES:
  28.1% Some college+
  Income not reported
Cancer History:
  Not reported
Both seekers and those who had
surrogate seekers were more
likely to be up-to-date on CRC
screening.
CRC cancer screening
adherence was assessed.
CRC HINTS 1
(2003)
Shim (2006) US adults
(n=6,369)
Race/ethnicity:
  70.3% White
  12.7% Hispanic
SES:
  31.3% Some college+
Cancer History:
  12.0% Had cancer
  62.8% Family member
  had cancer
Cancer prevention knowledge,
lifestyle behaviors, and
screening adherence were
positively associated with
cancer information seeking and
scanning.

However, knowledge was
inversely associated with the
interaction of seeking*scanning
behaviors.
N/A – Seeking and scanning
behaviors were the outcomes of
interest
CRC,
breast,
and
prostate
HINTS 1
(2003)
Finney-Rutten (2005) 50+ year old
males
(927)
Race/ethnicity:
  79.5% NH White
  7.0% Hispanic
SES:
  27.8% ≤$25,000
  49.6% Some college+
Cancer History:
  Not reported
Attention/seeking was not
associated with PSA testing
PSA testing Prostate
cancer
HINTS 1
(2003)

Footnotes:

a

Mean ± Standard Error;

b

Mean ± Standard Deviation;

c

Includes cohabitating (or living with a partner);

d

Does not include vocational/technical training;

AOR=adjusted odds ratio with 95% confidence interval; CRC=colorectal cancer; FOBT=fecal occult blood test; NH=non-Hispanic; NR=not reported; STI=sexually transmitted infection |

*

p<0.05;

**

p<0.01;

***

p<0.001