Fig. 3.

Near Infrared fluorescent (NIRF) images of the tumor xenografts. Images of the mice injected with Cy5.5-Lactoferrin conjugated NPs, with (a) and without (b) a permanent magnet placed adjacent to the tumor xenograft on the right side flank, compared with mice injected with Cy5.5-labeled NPs, without using lactoferrin and magnetic targeting (c). (d) Higher magnification sagittal and coronal images of the tumors, 2h after magnetic targeting. Three mice were used for each condition and pre-injection and post-injection (1 and 2h) images were captured from four different mice positions to show NPs accumulation in tumors clearly (see additional mice images in Figs. S4–S8).