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. 2018 Jul 26;6:e5245. doi: 10.7717/peerj.5245

Table 2. Changes of differentially expressed proteins of E. coli TG1 following exposure to cadmium.

Protein Up(+)/Down(−) regulation (fold)
TG1 carrying pUC19 plasmid TG1 expressing GFP TG1 expressing His6GFP TG1expressing OmpA TG1 expressing His-OmpA
Energy metabolism
Glycolysis
Glyceraldehyde-3-phosphate dehydrogenase (1) −2.02 −1.84 Absence +2.69 Absence
Glyceraldehyde-3-phosphate dehydrogenase (2) +1.75 +1.65 −1.06 −2.29 +1.63
Tricarboxylic acid cycle
Aconitase −1.20 No change Absence No change Absence
Glycerol uptake and lipolysis
Glycerol kinase −1.60 +1.73 +1.92 +1.43 +1.33
Protein biosynthesis machinery
Translation elongation factor-Ts +2.12 +1.84 +1.35 −0.39 +1.37
Transporters
Oligopeptide-binding protein −1.65 +1.37 −1.34 +1.22 +1.21
Amino acid ABC transporter substrate-binding protein −1.42 +1.37 +1.29 Not detectable +1.24
H+-transporting ATPase +2.69 −1.09 +1.30 −2.64 No change
ATP synthase F1, beta subunit +1.32 +1.26 +1.08 +1.86 −1.44
Stress defense mechanism
MnSOD +2.20 +1.29 −1.65 Not detectable +2.08
Alkyl hydroperoxide reductase −1.15 +1.71 −1.10 +1.52 −1.01
DNA starvation/stationary phase protection protein; Dps −3.29 Low amount −1.35 Low amount −1.05
Others
Ribosomal protein L9 +2.08 +1.33 −1.29 +1.42 +1.57
GFP Not detectable −1.45 Not detectable Not detectable Not detectable
His6GFP Not detectable Not detectable −2.24 Not detectable Not detectable
Disulfide isomerase I −1.71 Not determined −1.85 Not determined −1.36
OmpA (1) −1.68 −1.26 −1.40 −1.35 Absence
OmpC precursor −1.15 −1.31 −1.56 +1.32 +2.11
OmpF −1.18 Absence Absence No change Absence