Table 1.

Patient characteristics by baseline HDL-c level (in mg/dl) in those with CKD

Variable	Overall (N=38377)	≤30 (N=2463)	31–40 (N=7530)	41–50 (N=10369)	51–60 (N=8223)	>60 (N=9792)	p-value
Age	71.7+11.2	68.8+12.1	70.3+11.2	71.4+11.1	72.6+10.9	73.1+11.2	<0.001a
Male gender, %	44.2	70.2	64.7	49.6	36.5	22.7	<0.001c
African American,%	12.0	7.1	8.7	10.4	12.5	6.9	<0.001c
Smoking							<0.001c
No	81.3	60.6	76.0	82.1	85.1	86.6
Yes	7.0	9.0	8.6	7.2	5.9	5.9
Missing	11.7	30.4	15.4	10.7	9.0	7.6
BMI							<0.001c
<18.5 kg/m2	0.88	0.53	0.39	0.56	0.72	1.8
18.5–24.9 kg/m2	20.4	13.4	13.6	15.8	20.7	32.1
25–29.9 kg/m2	34.9	30.2	33.1	35.8	36.3	35.3
30–34.9 kg/m2	22.8	25.2	27.3	24.3	22.6	17.1
35–39.9 kg/m2	10.4	13.7	12.8	11.7	9.7	6.8
>40 kg/m2	7.3	9.5	8.9	8.2	7.2	4.6
Missing	3.4	7.6	3.9	3.6	2.7	2.3
eGFR, ml/min/1.73 m2	48.7+9.8	45.9+11.0	48.0+10.1	48.7+9.9	49.1+9.5	49.5+9.3	<0.001a
eGFR categories							<0.001c
45–59	71.5	61.2	68.9	71.5	73.3	74.5
30–44	22.1	27.5	23.5	22.0	21.3	20.5
15–29	6.4	11.3	7.6	6.4	5.4	5.0
Diabetes, %	29.8	32.4	37.8	33.2	27.9	20.8	<0.001c
Hypertension, %	87.2	66.1	83.6	88.6	90.2	91.5	<0.001c
CAD, %	24.2	26.3	30.9	26.4	23.0	17.3	<0.001c
CHF, %	7.8	11.2	9.9	7.8	6.4	6.5	<0.001c
Cerebrovascular
disease, %	10.4	8.4	10.6	10.8	10.8	9.9	0.002c
Peripheral vascular
disease, %	3.7	4.5	4.2	3.8	3.4	3.2	<0.001c
Hyperlipidemia, %	89.0	75.6	87.0	89.4	90.7	91.9	<0.001c
ACEI/ARBs, %	66.6	58.5	70.4	69.4	67.3	62.1	<0.001c
Statin use, %	65.8	52.6	66.3	69.2	69.3	61.9	<0.001c
Beta-Blocker use, %	55.7	56.4	62.1	57.9	55.2	48.5	<0.001c
Diuretic use, %	67.5	58.3	66.3	69.3	68.2	68.2	<0.001c
SBP (mm Hg)	130.2+19.0	127.5+20.2	129.5+19.2	130.0+19.0	130.4+18.7	131.1+18.7	<0.001a
DBP (mm Hg)	73.1+11.0	71.4+11.8	72.7+11.3	73.1+11.0	73.2+10.7	73.5+10.9	<0.001a
Serum albumin	4.1+0.44	3.8+0.61	4.1+0.45	4.1+0.42	4.2+0.39	4.2+0.39	<0.001a
Hemoglobin	13.0+1.7	12.7+2.0	13.1+1.9	13.1+1.8	13.0+1.6	12.9+1.5	<0.001a
Serum triglycerides	127.0[90.0,180.0]	175.0[118.0,263.0]	160.0[113.0,223.0]	138.0[100.0,187.0]	119.0[88.0,162.0]	97.0[73.0,131.0]	<0.001b
Total cholesterol	179.9±45.0	150.5±49.4	164.6±42.1	175.6±42.0	184.3±41.9	199.9±42.0	<0.001a
LDL cholesterol	98.3±36.1	80.9±40.8	90.9±33.7	98.5±35.1	101.7±36.1	103.7±36.0	<0.001a
Proteinuria, %	24.8	34.4	29.1	25.1	22.6	20.1	<0.001c
Malignancy, %	18.6	14.9	18.1	18.8	19.8	18.9	<0.001c
Insurance							<0.001c
Medicaid	0.30	0.41	0.31	0.36	0.26	0.23
Medicare	79.4	74.1	76.5	78.7	81.5	82.0
Missing	3.4	6.2	3.7	3.5	3.1	2.7
Other	16.9	19.3	19.5	17.5	15.2	15.1

Values presented as mean+SD, percent, or median [P25, P75]

^aANOVA,

^bKruskal-Wallis test,

^cChi-square test