TABLE 5.
Association between SDOCT subfield measurements and demographic or clinical findings using repeated-measures ANOVA, with sickle cell types controlled (513 eyes in 260 patients)*
| SDOCT Subfield |
Patient Age |
Smoking | Stage | Hydroxy urea use |
Caliber of Anastamoses |
Tortuosity | Sea fan | Hemorrhage | Sunburst |
|---|---|---|---|---|---|---|---|---|---|
| Central | .017 | .214 | .051 | .256 | .327 | .312 | .455 | .434 | .320 |
| Nasal inner | <.001 | .281 | .445 | .885 | .950 | .072 | .105 | .012 | .287 |
| Superior inner | <.001 | .165 | .164 | .502 | .846 | .105 | .024 | .008 | .047 |
| Temporal inner | <.001 | .069 | .016 | .760 | .464 | .761 | .001 | .021 | .020 |
| Inferior inner | <.001 | .162 | .509 | .670 | .711 | .019 | .024 | .184 | .107 |
| Nasal outer | <.001 | .049 | .435 | .503 | .829 | .016 | .097 | .043 | .164 |
| Superior outer | <.001 | .260 | .515 | .413 | .384 | .037 | .450 | .022 | 0.014 |
| Temporal outer | .010 | .175 | .061 | .125 | .494 | 0.520 | .003 | .521 | .006 |
| Inferior outer | <0.001 | .064 | .666 | .149 | .667 | .025 | .106 | .485 | .024 |
ANOVA, analysis of variance; SDOCT, spectral domain optical coherence tomography.
*
P values <.006 (ie, 0.05/9) for the associations are considered significant based on Bonferroni correction and are in bold type.