Figure 8.
Effects of incremental IH episodes on leptin levels in the liver of neonatal rats at P7 (7D-IH), P14 (14D-IH), or P21-IHR. Animals recovering from 7D-IH were placed in RA from P7-P21 and animals recovering from 14D-IH were placed in RA from P14-P21. Animals randomized to IH were exposed to brief clustered IH episodes during 50% O2. Animals randomized to hyperoxia were exposed to 50% O2 only. RA controls remained in atmospheric O2. Data are presented as mean±SEM (n=8 samples/group).