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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: J Clin Lipidol. 2018 Apr 12;12(4):849–856. doi: 10.1016/j.jacl.2018.04.001

Table 1.

Kinetics of Clearance of HDL and nHDL*

Human Plasma Lifetime Mouse Plasma Lifetime
t1/2 FCR t1/2 FCR
HDL-apo AI 5.8 d (83) 0.12/d 5.8 h (84) 0.12/h
HDL-FC 7–8 min (40) 0.09/min 3.2 min (39) 0.22/min
HDL-CE 0.92 d (85) 0.75/d 3.3–3.5 h(40,42,43,85) 0.21/h
nHDL-FC - 5.2 min (1) 0.13/min
nHDL-PL - 2.0 min (1) 0.35/min
nHDL-apo AI - 7.7 h (1) 0.09/h
*

Fractional catabolic rate (FCR) = ln2/t1/2.