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. 2018 Jul 23;12:56. doi: 10.3389/fncir.2018.00056

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Copyright © 2018 He, Arroyo, Cantu, Goel and Portera-Cailliau.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Loss of synchronous spontaneous activity of L2/3 neurons in developing barrel cortex coincides with their ability to respond to whisker stimuli between P11 and P15. (A) Overlay of fluorescent traces of spontaneous activity of the neurons in Figure 6A field of view. Different color traces are from different neurons (n = 24). (B) Neuronal activity is time-locked to whisker stimulation at P15, but not at P11. Traces were aligned to whisker stimulus and averaged over all 10 stimuli (bold traces).