Table 2.

Over view of 13 kampo medicines introduced in CPG, its indications and components referred from STORK (40), and its characteristics in kampo theory.

		Kampo medicine
		orengedokuto	goshajinkigan	tokiinshi	hachimijiogan	rokumigan	shoseiryuto	bakumondoto	rikkunshito	keishikashakuyakuto	daiokanzoto	daikenchuto	yokukansan	hangekobokuto
Clinical manifestation of frailty according to the traditional concept	Anorexia							◦	◦			◦	◦
	Sarcopenia		◦		◦	◦
	Cognition		◦		◦	◦
	Dementia	◦											◦
	Fatigue								◦					◦
	Weakness		◦		◦	◦			◦
	Pain		◦		◦					◦		◦
	Dysfunction of
	Respiration						◦	◦						◦
	Circulation		◦	◦	◦	◦
	Gastro-intestine							◦	◦	◦	◦	◦		◦
	Urinary		◦		◦	◦
	Musculoskeletal		◦		◦	◦
	Skin	◦	◦	◦	◦	◦
Indications		The relief of the following symptoms of those patients who have ruddy face with comparatively strong constitution, a touch of hot flushes, and a tendency to irritability: nose bleeding, hypertension, insomnia, neurosis, gastritis, alcoholic hangover, climacteric disturbance and automatic imbalance syndrome peculiar to women resembling climacteric disturbance, dizziness, palpitation, eczema or dermatitis and pruritus cutaneous	The relief of the following symptoms of those patients with decreased urine volume or polyuria sometimes having dry mouth who are easily fatigued and easily feel cold in the extremities: Leg pain, low back pain, numbness, blurred vision in old patients, pruritus, dysuria, frequent urination and edema	The relief of the following symptoms of those patients with oversensitivity to cold: Chronic eczema (with little exudation) and itching	The relief of the following symptoms of those patients with severe fatigue or malaise, decreased urinary output or increased urinary frequency, dry mouth, and alternate cold and hot feeling in the extremities: Nephritis, diabetes mellitus, impotence, sciatica, low back pain, beriberi, cystorrhea, prostatic hypertrophy and hypertension	The relief of the following symptoms of those patients with decreased urine volume or polyuria sometimes having dry mouth who are easily fatigued: Dysuria, frequent urination, edema and pruritus	Watery sputum, watery nasal discharge, nasal obstruction, sneezing, stridor, coughing, lacrimation in the following diseases: Bronchitis, bronchial asthma, rhinitis, allergic rhinitis, allergic conjunctivitis, and common cold	The relief of the following symptoms: Coughing with a hard, obstructive sputum, bronchitis, and bronchial asthma	The relief of the following symptoms of those patients with weak stomach, loss of appetite and full stomach pit, and those who are easily fatigued, anemic and likely to have cold limbs: Gastritis, gastric atony, gastroptosis, maldigestion, anorexia, gastric pain, vomiting	The relief of the following symptoms of those patients with abdominal distension: Tenesmus alvi and abdominal pain	Constipation	The relief of abdominal cold feeling and pain accompanied by abdominal flatulence	The relief of the following symptoms of those patients with delicate constitution and nervousness: Neurosis, insomnia, night cry in children, and peevishness in children	The relief of the following symptoms of those patients who have depressed feelings and a feeling of foreign body in the throat and oesophagus and who sometimes have palpitation, dizziness, nausea, etc.: Anxiety neurosis, nervous gastritis, hyperemesis gravidarum, coughing, hoarseness, nervous oesophageal stricture, and insomnia
Components of kampo medicine		JP Scutellaria Root	JP Rehmannia Root	JP Japanese Angelica Root	JP Rehmannia Root	JP Rehmannia Root	JP Pinellia Tuber	JP Ophiopogon Tuber	JP Atractylodes Lancea Rhizome	JP Peony Root	JP Rhubarb	JP Processed Ginger	JP Atractylodes Lancea Rhizome	JP Pinellia Tuber
		JP Coptis Rhizome	JP Achyranthes Root	JP Rehmannia Root	JP Cornus Fruit	JP Cornus Fruit	JP Processed Ginger	JP Brown Rice	JP Ginseng	JP Cinnamon Bark	JP Glycyrrhiza	JP Ginseng	JP Poria Sclerotium	JP Poria Sclerotium
		JP Gardenia Fruit	JP Cornus Fruit	JP Tribulus Fruit	JP Dioscorea Rhizome	JP Dioscorea Rhizome	JP Glycyrrhiza	JP Pinellia Tuber	JP Pinellia Tuber	JP Jujube		JP Zanthoxylum Fruit	JP Cnidium Rhizome	JP Magnolia Bark
		JP Phellodendron Bark	JP Dioscorea Rhizome	JP Peony Root	JP Alisma Rhizome	JP Alisma Rhizome	JP Cinnamon Bark	JP Jujube	JP Poria Sclerotium	JP Glycyrrhiz		JP Koi	JP Uncaria Hook	JP Perilla Herb
			JP Plantago Seed	JP Cnidium Rhizome	JP Poria Sclerotium	JP Poria Sclerotium	JP Schisandra Fruit	JP Glycyrrhiza	JP Jujube	JP Ginger			JP Japanese Angelica Root	JP Ginger
			JP Alisma Tuber	JP Saposhnikovia Root and Rhizome	P Moutan Bark	JP Moutan Bark	JP Asiasarum Root	JP Ginseng	JP Citrus Unshiu Peel				JP Bupleurum Root
			JP Poria Sclerotium	JP Polygonum Root	JP Cinnamon Bark		JP Peony Root		JP Glycyrrhiza				JP Glycyrrhiza
			JP Moutan Bark	JP Astragalus Root	JP Powdered Processed Aconite Root		JP Ephedra Herb		JP Ginger
			JP Cinnamon Bark	JP Schizonepeta Spike
			JP Powdered Processed Aconite Root	JP Glycyrrhiza

JP, The Japanese Pharmacopoeia.