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. 2018 Jul 23;9:1691. doi: 10.3389/fimmu.2018.01691

Table 1.

Overview of complement inhibitors used in this study.

Inhibitor Type Key references
C3b-binding molecules
Cp40 Compstatin (analog Cp40) Cyclic peptide (39, 41, 42)
CRIg Complement receptor of immunoglobulin family Human complement regulator protein (31, 32)
FH Factor H Human complement regulator protein (33, 34, 43, 44)
FHR5 Factor H related-protein 5 Human complement regulator protein (35, 45)
Efb-C (C-terminal region of) Extracellular fibrinogen binding protein Staphylococcus aureus immune evasion protein (21, 36, 46)
Ecb Extracellular complement binding protein (also known as Ehp) Staphylococcus aureus immune evasion protein (16, 23)
C5-binding molecules
SSL7 Staphylococcal superantigen-like protein 7 Staphylococcus aureus immune evasion protein (37, 47, 48)
OmCI Ornithodoros moubata complement inhibitory protein Ornithodoros moubata immune evasion protein (20, 49, 50)
Eculizumab Also known as Soliris Humanized monoclonal antibody (38, 51, 52)
C4b-binding molecules
C4BP C4b-binding protein Human complement regulator protein (40, 53, 54)