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. 2018 Jul 23;9:1720. doi: 10.3389/fimmu.2018.01720

Figure 5.

Figure 5

Lack of glucocorticoid-induced leucine zipper (GILZ) exacerbates 2,4-dinitrobenzene sulfonic acid (DNBS)-induced colitis. (A) Loss of body weight in wild-type (WT) and gilz B cKO mice treated intrarectally with vehicle (Sham) or DNBS. (B) Daily measurement of total disease score in WT and gilz B cKO mice during DNBS-induced colitis. (C) Colon weight/length ratio of WT and gilz B cKO mice intrarectally administered with vehicle (Sham) or DNBS. (D) Representative macroscopic images of the colon of WT and gilz B cKO mice intrarectally administered with vehicle (Sham) or DNBS are shown (n = 9). Statistical analysis was performed using the unpaired Student’s t-test (*p < 0.05, ***p < 0.001).