Table 3.
Effects of pretreatment with FPLR on the levels of liver SOD, CAT, GSH, and MDA in CCl4-treated mice ( ± SD, n = 10)
Groups | SOD (U/mg prot) | CAT (U/mg prot) | GSH (mg/g prot) | MDA (nmol/mg prot) |
---|---|---|---|---|
Normal control | 59.84 ± 5.98a | 38.55 ± 2.78a | 4.65 ± 0.73a | 1.92 ± 0.52d |
CCl4-treated | 45.11 ± 4.22d | 20.84 ± 2.14d | 1.97 ± 0.48c | 3.99 ± 0.93a |
Bifendate (100 mg/kg bw) + CCl4 | 55.04 ± 5.27ab | 32.35 ± 2.55b | 4.20 ± 0.45ab | 2.47 ± 0.39cd |
FPLR (50 mg/kg bw) + CCl4 | 48.11 ± 2.36cd | 26.95 ± 1.36c | 3.56 ± 0.73b | 3.32 ± 0.64b |
FPLR (100 mg/kg bw) + CCl4 | 51.14 ± 4.46bcd | 28.89 ± 2.24bc | 3.88 ± 0.79b | 2.86 ± 0.78bc |
FPLR (200 mg/kg bw) + CCl4 | 53.21 ± 3.66bc | 31.92 ± 4.61b | 4.08 ± 0.73ab | 3.16 ± 0.51b |
Data are shown as mean values ± SD for the 10 mice in each group. Values within a column with different letters indicate significant difference among different groups at p < 0.05.