Table 1.
Characteristics of Study Participants Without and With Recurrent CHD Events in the REGARDS Cohort
| Characteristic | Total Mean±SD or n (%) | No Recurrent CHD Event Mean±SD or n (%) | Recurrent CHD Event Mean±SD or n (%) | P Difference |
|---|---|---|---|---|
| N=3562 | n=2981 | n=581 | ||
| Age, y | 68.6±8.9 | 68.3±8.8 | 70.0±9.2 | <0.001 |
| Sex, male | 2179 (61.2) | 1772 (59.4) | 407 (70.1) | <0.001 |
| Race, black | 962 (27.0) | 812 (27.2) | 150 (25.8) | 0.48 |
| Education, did not graduate from high school | 477 (13.4) | 383 (12.9) | 94 (16.2) | 0.031 |
| Household income <$20 000/y | 686 (21.7) | 557 (21.1) | 129 (24.4) | 0.092 |
| Resident of stroke belta | 2007 (56.3) | 1692 (56.8) | 315 (54.2) | 0.26 |
| Current smoker | 527 (14.9) | 434 (14.6) | 93 (16.0) | 0.38 |
| Physically inactiveb | 1276 (36.3) | 1020 (34.6) | 256 (44.9) | <0.001 |
| Total energy intake, kcal/day | 1685±688 | 1684±687 | 1694±693 | 0.74 |
| Body mass index, kg/m2 | 29.2±5.8 | 29.0±5.9 | 29.9±5.7 | 0.002 |
| Waist circumference, cm | 98.9±15.4 | 98.3±15.4 | 102.2±15.3 | <0.001 |
| Systolic blood pressure, mm Hg | 129.2±16.9 | 128.6±16.7 | 132.3±17.9 | <0.001 |
| Hypertensionc | 2506 (70.7) | 2058 (69.3) | 448 (77.6) | <0.001 |
| Dyslipidemiad | 2716 (78.0) | 2251 (77.2) | 465 (81.9) | 0.015 |
| Diabetes mellituse | 1030 (29.8) | 786 (27.3) | 244 (42.7) | <0.001 |
| Antihypertensive use | 2298 (66.9) | 1887 (65.9) | 411 (72.2) | 0.003 |
| Statin use | 2109 (59.2) | 1759 (59.0) | 350 (60.2) | 0.58 |
| Regular aspirin use | 2512 (70.5) | 2077 (69.7) | 435 (75.0) | 0.010 |
| Oral antidiabetic use | 759 (21.3) | 582 (19.5) | 177 (30.5) | <0.001 |
| Insulin use | 334 (9.9) | 245 (8.7) | 89 (16.3) | <0.001 |
| PCS‐12 | 43.0±11.5 | 43.5±11.4 | 40.2±11.4 | <0.001 |
CHD indicates coronary heart disease; PCS, Physical Component Summary; REGARDS, Reasons for Geographic and Racial Differences in Stroke study; SD, standard deviation.
Stroke belt consists of North Carolina, South Carolina, Georgia, Tennessee, Alabama, Mississippi, Arkansas, and Louisiana.
Physically active defined as ≥4 days of exercise (enough to work up a sweat) per week.
Hypertension defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg or self‐reported current use of medication to control blood pressure.
Dyslipidemia defined as total cholesterol ≥6.22 mmol/L (240 mg/dL) and/or low‐density lipoprotein cholesterol ≥4.14 mmol/L (160 mg/dL) and/or high‐density lipoprotein cholesterol ≤1.04 mmol/L (40 mg/dL) or self‐reported current use of medication to control cholesterol.
Diabetes mellitus defined as fasting glucose ≥6.99 mmol/L (126 mg/dL) and/or nonfasting glucose ≥11.10 mmol/L (200 mg/dL) or self‐reported current use of medication to control blood sugar.