Table 2.
Unadjusted Univariate Associations of Preoperative Biomarker Measurements and Postoperative In‐Hospital Outcomes
| Outcomes (OR [95% CI]) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| In‐Hospital Mortality | New AFib | New Dialysis | Mediastinitis | Transient Ischemic Attack | Low Cardiac Output | Stroke | Pneumonia | Bleeding Complications | Leg Infection | |
| Gal3 | ||||||||||
| Median 1 | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) |
| Median 2 | 1.68 (0.82–3.47) | 1.44 (1.13–1.84) | 1.25 (0.38–4.13) | 0.57 (0.19–1.71) | 1.77 (0.29–10.64) | 1.69 (1.11–2.57) | 1.75 (0.83–3.70) | 1.59 (0.81–3.13) | 1.30 (0.57–2.99) | 3.97 (1.10–14.29) |
| Tercile 1 | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) |
| Tercile 2 | 1.13 (0.43–2.95) | 1.35 (0.99–1.84) | 0.50 (0.09–2.74) | 0.67 (0.19–2.40) | 1.11 (0.16–7.94) | 1.55 (0.89–2.71) | 2.04 (0.82–5.10) | 0.58 (0.23–1.48) | 0.62 (0.20–1.91) | 1.60 (0.27–9.63) |
| Tercile 3 | 1.91 (0.80–4.54) | 1.54 (1.14–2.09) | 1.35 (0.36–5.04) | 0.70 (0.20–2.49) | 0.65 (0.06–7.17) | 2.04 (1.20–3.47) | 1.29 (0.48–3.49) | 1.44 (0.68–3.04) | 1.24 (0.49–3.18) | 5.21 (1.12–24.27) |
| NT‐proBNP | ||||||||||
| Median 1 | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) |
| Median 2 | 5.53 (2.12–14.44) | 1.41 (1.10–1.80) | 11.19 (1.43–87.74) | 2.83 (0.88–9.07) | 0.48 (0.05–4.32) | 3.11 (1.95–4.96) | 2.84 (1.25–6.41) | 1.78 (0.90–3.55) | 1.36 (0.59–3.12) | 0.84 (0.29–2.42) |
| Tercile 1 | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) |
| Tercile 2 | 3.52 (0.73–17.04) | 1.48 (1.08–2.02) | 0.20 (0.04–0.91) | 2.08 (0.38–11.41) | 0.44 (0.05–4.26) | 3.11 (1.45–6.69) | 0.57 (0.17–1.96) | 1.00 (0.37–2.68) | 1.44 (0.54–3.83) | 1.07 (0.31–3.74) |
| Tercile 3 | 11.89 (2.79–50.73) | 1.60 (1.18–2.18) | 1 (REF) | 4.74 (1.00–22.48) | 0.84 (0.09–8.16) | 7.66 (3.76–15.59) | 2.79 (1.16–6.70) | 2.54 (1.11–5.82) | 0.91 (0.30–2.72) | 0.93 (0.25–3.50) |
| ST‐2 | ||||||||||
| Median 1 | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) |
| Median 2 | 4.43 (1.81–10.82) | 1.12 (0.87–1.42) | 2.82 (0.74–10.68) | 6.37 (1.42–28.60) | 0.84 (0.14–5.09) | 1.64 (1.07–2.49) | 3.34 (1.43–7.84) | 2.30 (1.12–4.71) | 0.94 (0.41–2.13) | 2.60 (0.81–8.35) |
| Tercile 1 | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) | 1 (REF) |
| Tercile 2 | 1.60 (0.52–4.93) | 1.28 (0.94–1.73) | 2.09 (0.19–23.14) | 0.71 (0.25–2.08) | 0.34 (0.04–3.31) | 1.66 (0.95–2.90) | 6.58 (1.48–29.32) | 2.63 (0.93–7.42) | 0.44 (0.13–1.42) | 6.09 (0.73–50.83) |
| Tercile 3 | 3.88 (1.44–10.48) | 1.32 (0.98–1.79) | 8.83 (1.10–70.92) | 1 (REF) | 0.45 (0.05–4.36) | 2.14 (1.25–3.66) | 7.58 (1.43–7.84) | 3.67 (1.35–9.97) | 1.15 (0.46–2.85) | 7.49 (0.92–61.20) |
Model adjusts for age, sex, ejection fraction <40%, presence of any disease, left main stenosis >50%, white blood cell count, prior myocardial infarction, prior coronary artery bypass graft surgery, presence of any vascular disease, presence of diabetes mellitus, history of renal failure, chronic obstructive pulmonary disease, and urgent and emergent priority. CI indicates confidence interval; Median 1, below median values; Median 2, above median values; New AFib, new atrial fibrillation; OR, odds ratio.