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. 2018 Jul 9;7(14):e009289. doi: 10.1161/JAHA.118.009289

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Desmin expression in D7‐Des Tg mice hearts. A, Western blot analysis of desmin and αB‐crystallin protein expression in the soluble and insoluble protein fractions derived from 6‐month‐old D7‐Des Tg and Ntg hearts. n=5 mice per group. B, Confocal microscopy images of immunostaining of desmin (red) in heart sections showing aberrant desmin aggregates in D7‐Des Tg cardiomyocytes (Scale bars: 5 μm). CryAB indicates αB‐Crystallin; D7‐Des Tg, mutant desmin transgenic mouse; Ntg, non‐transgenic.