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Light micrographs of aortic valves at 2.5 to 4 months of age. A, Control valve. B, Velvet valve without echocardiographic evidence of significant aortic regurgitation (AR) or aortic stenosis (AS), designated as functionally normal (Nl). C, Velvet valve with severe AR and severe AS. Arrows indicate noncoplanar architecture of valve tissue. Differences in pigmentation between control valves and Velvet valves are not consistently observed.
