Table 2.

Associations Between Circulating Adipokine Concentrations and Echocardiographic Indices

	Cardiac Structural Measures				LV Function Measures
	Log‐LVMI		LAD		FS		Log‐E/e′
	Estimate	P Value	Estimate	P Value	Estimate	P Value	Estimate	P Value
Leptin	−0.037	<0.0001a	−0.039	<0.0001a	0.009	0.92	0.009	0.14
LR	0.009	0.002a	0.008	0.21	−0.107	0.08	−0.016	0.0002a
FLI	−0.024	<0.0001a	−0.028	0.001a	0.050	0.52	0.014	0.0055
FABP4	−0.019	<0.0001a	−0.010	0.18	0.047	0.52	0.002	0.61
RBP4	0.012	<0.0001a	0.025	0.0001a	−0.068	0.29	−0.007	0.09
Fetuin‐A	−0.002	0.45	−0.006	0.24	0.11	0.04	0.005	0.13
Adiponectin	−0.002	0.57	0.008	0.20	−0.061	0.34	0.004	0.26

Estimates are β coefficients per 1‐SD increase for each within‐sex standardized adipokine. Models are adjusted for cohort, age, sex, height, weight, systolic blood pressure, diastolic blood pressure, heart rate, diabetes mellitus, antihypertensive treatment, smoking, serum creatinine, high‐density lipoprotein, low‐density lipoprotein, and triglycerides. FABP4 indicates fatty acid–binding protein 4; FLI, free leptin index; FS, fractional shortening; LAD, left atrial diameter in end systole; LR, leptin receptor; LV, left ventricular; LVMI, LV mass index; RBP4, retinol‐binding protein 4.

^aBonferroni‐corrected P≤0.002.