Table 3.

Hormonal influences on the emotion regulation network.

	Low P			High P
		r	p		r	p
ESTRADIOL
Activity				Amygdala	−0.670	0.048
Connectivity				OFC-Amygdala	−0.799	0.010*
				OFC-NAc	0.801	0.009*
PROGESTERONE
Activity				Amygdala	−0.687	0.041
				OFC	−0.674	0.046
Connectivity				IFG-Amygdala	−0.842	0.004*
TESTOSTERONE
Activity	Amygdala	−0.641	0.046
	OFC	−0.689	0.027
Connectivity	OFC-NAc	−0.697	0.025

ROI analyses were performed to establish whether serum hormone levels related to activity within and connectivity between four key regions of the emotion regulation network. Pearson's partial correlations were performed to investigate the relationships controlling for repeated measures. All relationships significant at p < 0.05 are shown; those that survive correction for multiple comparisons (four ROIs: p < 0.05/4 = 0.0125; four connectivity relationships: p < 0.05/4 = 0.0125) are highlighted with an asterisk.

P, progesterone; OFC, orbitofrontal cortex; IFG, inferior frontal gyrus; NAc, nucleus accumbens.