Table 1.

Concentrations of ascorbic acid (AA), 5-Fluorouracil (5-FU), oxaliplatin (Oxa), and irinotecan (Iri) present in each mixture, for f = 0.75, to evaluate cell proliferation of C2BBe1, LS1034, and WiDr cell lines.

			AA + 5-FU		AA + Oxa		AA + Iri
Cell line	Conditions	Variations of Z (aZ)	[AA] (mM)	[5-FU] (μM)	[AA] (mM)	[Iri] (μM)	[AA] (mM)	[Oxa] (μM)
C2BBe1	B1	0.25Z	0.15	1.26	0.15	0.14	0.15	0.74
	B2	0.5Z	0.31	2.51	0.31	0.28	0.31	1.48
	B3	Z	0.61	5.03	0.61	0.55	0.61	2.97
	B4	2Z	1.23	10.05	1.23	1.11	1.23	5.93
	B5	4Z	2.45	20.10	2.45	2.21	2.45	11.87
	B6	6Z	–	–	3.68	3.32	3.68	17.80
	B7	8Z	4.91	40.20	4.91	4.42	4.91	23.73
LS1034	B1	0.25Z	1.01	0.42	1.01	0.13	1.01	0.30
	B2	0.5Z	2.01	0.84	2.01	0.25	2.01	0.59
	B3	Z	4.03	1.67	4.03	0.50	4.03	1.19
	B4	1.5Z	6.04	2.51	6.04	0.75	6.04	1.78
	B5	2Z	8.05	3.35	8.05	1.01	8.05	2.38
	B6	3Z	12.08	5.02	12.08	1.51	12.08	3.57
	B7	4Z	–	–	16.10	2.01	16.10	4.76
WiDr	B1	0.25Z	1.11	0.18	1.11	0.51	1.11	0.11
	B2	0.5Z	2.21	0.35	2.21	1.03	2.21	0.22
	B3	Z	4.43	0.71	4.43	2.05	4.43	0.44
	B4	1.5Z	6.64	1.06	6.64	3.08	6.64	0.66
	B5	2Z	8.86	1.41	8.86	4.11	8.86	0.88
	B6	3Z	13.28	2.12	13.28	6.16	13.28	1.33
	B7	4Z	–	–	17.71	8.21	17.71	1.77

‘a’ Represents the increasing values multiplied by the constant Z to obtain the different combinations of the ray design.