Figure 3.
HP diet increases mean 24-hour SBP, DBP, and pulse rate with preserved circadian oscillation, and in parallel with significant increases in urinary metanephrine and normetanephrine excretion rates. Vitamin D does not reverse the hypertensiongenic effect in the short term (5 weeks). (A) See Figure 2 legend for description of periods. All values are means of three consecutive daily measurements during the last 3 days of each period. Recovery values are from measurements 2 months after week 11 to show reversibility and with the subjects on regular diet only. *P at least <0.05 for both intra- and intergroup comparisons. (B) Effect of HP diet on day and night mean arterial BP and mean pulse rates. *P at least <0.05 for the comparisons to both baseline and recovery. (C) Per subject changes in MAP in the HP group. BL, baseline; D3, vitamin D3; HP, HP diet; La, lanthanum; LP, LP diet; MAP, mean arterial pressure; NaCl, sodium chloride; NaP, neutral sodium phosphate; PTH, parathyroid hormone; RD, regular diet; REC, recovery; W6 and W11, week 6 and 11, respectively.