Table 6.
Effect of HP and LP dietary conditions without and with vitamin D3 on fasting markers of cardiovascular risk, oxidative stress, and aging as well as the calcifying propensity of blood (T50)
| Variable | Insulin (IU/L) | HOMA-IR | Glucose (mmol/L) | HbA1C (%) | hsCRP (mg/dl) | Fibrinogen (mmol/L) | D-Dimers (μg/ml) | Homocysteine (μmol/L) | Albumin (g/L) | Triglycerides (mmol/L) | Total Cholesterol (mmol/L) | oxLDL (ng/ml) | Antiox. Capacity (μmol/L) | Lipid Peroxides (μmol/L) | Superoxide Dismutase (ng/ml) | 8-oxo-2deoxy guanosine (urine) (μg/L) | T50a (Min) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HP baseline | 9.2±1.4 | 1.71±0.17 | 3.99±0.33 | 5.2±0.2 | 1.38±0.11 | 2.9±0.2 | 0.22±0.06 | 11.0±1.4 | 46.0±1.1 | 0.99±0.09 | 4.44±0.20 | 385±27 | 253±22 | 385±38 | 4.26±0.31 | 3.39±0.21 | 340±32 |
| LP baseline | 9.4±1.2 | 1.74±0.15 | 4.02±0.31 | 5.2±0.2 | 1.42±0.12 | 2.9±0.2 | 0.24±0.07 | 10.8±1.5 | 45.9±1.2 | 1.00±0.07 | 4.45±0.23 | 419±30 | 256±25 | 398±33 | 4.27±0.27 | 3.39±0.22 | 300±34 |
| HP W6 | 8.2±0.9 | 1.44±0.14 | 3.87±0.38 | 5.1±0.3 | 2.10±0.16 | 2.9±0.1 | 0.20±0.05 | 12.2±1.3 | 46.9±1.0 | 0.95±0.06 | 4.51±0.20 | 362±28 | 236±22 | 521b±42 | 4.84±0.30 | 5.55b±0.41 | 305±40 |
| LP W6 | 9.1±1.1 | 1.64±0.14 | 3.92±0.35 | 5.2±0.3 | 1.58±0.11 | 2.9±0.2 | 0.26±0.06 | 10.9±1.2 | 46.8±0.9 | 0.93±0.07 | 4.50±0.22 | 397±32 | 234±24 | 478b±44 | 4.72±0.26 | 5.98b±0.42 | 274±29 |
| HP plus D3 W11 | 9.4±1.2 | 1.92±0.24 | 4.16±0.25 | 5.1±0.2 | 1.39±0.12 | 2.8±0.1 | 0.28±0.05 | 12.0±1.3 | 46.0±0.9 | 0.97±0.06 | 4.50±0.24 | 435±33 | 240±21 | 449b±47 | 3.83±0.36 | 5.42b±0.44 | 308±39 |
| LP plus D3 W11 | 9.3±1.0 | 1.82±0.18 | 4.04±0.29 | 5.1±0.2 | 1.79±0.14 | 2.8±0.1 | 0.30±0.06 | 12.3±1.2 | 46.3±1.0 | 0.95±0.05 | 4.6±0.23 | 439±37 | 241±19 | 448b±45 | 4.43±0.41 | 6.00b±0.47 | 259±27 |
Values are mean±SEM. HOMA-IR, homeostatis model assessment insulin resistance; HbA1C, glycosylated hemoglobin; hsCRP, high-sensitivity C-reactive protein; oxLDL, oxidized low density lipoprotein; Antiox., antioxidant; W, week.
a
n=7 in both groups.
b
P<0.05 for the intragroup comparison with baseline.