Table 3.
No. | Hb, mmol/L | LDH, U/L | Platelets, ×109/L | Creatinine, μmol/L | C5b9 formation on HMEC-1, % of the control | |
---|---|---|---|---|---|---|
Resting | Activated | |||||
Eculizumab treatment | ||||||
2 | 7.2 | 135 | 199 | 297 | 21a | ND |
5 | 5.5 | 143 | 492 | ESRD | 0a | 0a |
6 | 6.3 | 154 | 298 | 243 | 17a | 14a |
9 | 5.5 | 179 | 291 | 315 | 0a | 24a |
11 | 6.8 | 138 | 216 | 132 | 8a | 29a |
No treatment | ||||||
8 | 7.0 | 239 | 333 | ND | 160 | 231a |
11 | 6.8 | 197 | 174 | 205 | 163 | 293a |
12 | 6.1 | 181 | 232 | 220 | 87 | 171a |
14 | 7.5 | ND | 198 | 98 | 116 | 248a |
Hb, hemoglobin; LDH, lactate dehydrogenase; HMEC-1, human microvascular endothelial cells of dermal origin; ND, not determined.
P value <0.05 versus control serum run in parallel.