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Calcineurin inhibitors may ameliorate anillin (ANLN)-mediated disease by targeting ANLN and mTOR expression. (A) Representative Western blot images of ANLN and mTOR protein amounts in GFP control– and VIVIT-expressing podocytes. (B and C) Quantification of Western blots revealed a significant decrease in (B) ANLN and (C) mTOR protein in VIVIT-expressing podocytes compared with GFP control podocytes (P<0.01 and P=0.03, respectively). tGFP, turbo GFP.
