Table 3. Variables associated with CDI after lung transplantation (N=229; p≤0.20)^a.

Variable	CDI N (%)	No CDI N (%)	OR (95% CI)	p-value
Risk Factors
Comorbidities
Gastroesophageal reflux disease	12 (40)	52 (26)	1.9 (0.9 – 4.2)	0.12
Other GI disease	5 (17)	15 (8)	2.5 (0.8 – 7.3)	0.15c
Severity of illness in 30 days before index date
ICU admission	11 (37)	48 (24)	1.8 (0.8 – 4.1)	0.14
Mechanical ventilation	11 (37)	48 (24)	1.8 (0.8 – 4.1)	0.14
Renal failure	3 (10)	3 (2)	7.3 (1.4 – 37.8)	0.031c
Symptomatic UTI	2 (7)	3 (2)	4.7 (0.7 – 29.2)	0.13c
Outcomes
ICU admissionb	3 (10)	8 (4)	2.7 (0.7 – 10.6)	0.16c
Mechanical ventilation	5 (17)	15 (8)	2.5 (0.8 – 7.3)	0.15c
Renal failure	3 (10)	4 (2)	5.4 (1.2 – 25.5)	0.050c
BSI	3 (10)	2 (1)	10.9 (1.7 – 68.5)	0.017c
Pneumonia	8 (27)	13 (7)	5.2 (1.9 – 13.9)	<0.001
Symptomatic UTI	2 (7)	3 (2)	4.7 (0.7 – 29.2)	0.13c

^aPotential risk factors and outcomes with p>0.20 not included in the table: Age, sex, race, coronary artery disease, congestive heart failure, peripheral vascular disease, other cardiovascular disease, COPD, asthma, other pulmonary disease, cirrhosis, chronic renal insufficiency, end state renal disease, hemodialysis, peritoneal dialysis, splenectomy, diabetes, autoimmune disease, HIV, HCV, HBV, other comorbid disease, no comorbid disease, all pre-transplant medications; dialysis, bloodstream infection, pneumonia, febrile neutropenia, viremia, or respiratory tract infection in 30 days before index date; dialysis, viremia, and respiratory tract infection in 30 days after index date.

^bICU admissions at index date are excluded.

^cFisher’s exact test.