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a, fluorescence emission spectra of bis-ANS binding to p53C at different GuHCl concentrations. b, CD measurements of p53C in the absence or presence of 0.5 or 0.8 m GuHCl. c–e, 1H-15N HSQC spectra of p53C in the absence and presence of 0.8 m (c), 1.2 m (d), and 2 m (e) GuHCl. a.u., arbitrary units.
