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. 2018 Jul 23;8:273. doi: 10.3389/fonc.2018.00273

Table 1.

Comparison patient and treatment characteristics of HPV negative and HPV positive patients.

HPV negative HPV positive P-value
PATIENT AND TREATMENT CHARACTERISTICS
Gender 0.347
Male 130/160 (81.25%) 76/100 (76.00%)
Female 30/160 (18.75%) 24/100 (24.00%)
Age 0.030
Median (IQR) 59.7 (54.0-65.8) 63.6 (54.9-70.1)
Smoking <0.001
mean pack years (SD) 38.8 (22.12) 22.6 (21.65)
Never smoker 3/160 (1.88%) 27/100 (27.00%)
≤ 10 Pack years 8/160 (5.00%) 14/100 (14.00%)
>10 Pack years 147/160 (91.87%) 56/100 (57.00%)
Unknown 2/160 (1.25%) 3/100 (3.00%)
Systemic Treatment 0.076
No 46/160 (28.75%) 31/100 (31.00%)
Cisplatin 97/160 (60.63%) 66/100 (66.00%)
EGFR-inhibitor 17/160 (17.00%) 3/100 (3.00%)
Comorbidity: ACE27 0.007
0 26/160 (16.25%) 31/100 (31.00%)
1 64/160 (40.00%) 37/100 (37.00%)
2 38/160 (23.75%) 24/100 (24.00%)
3 32/160 (20.00%) 8/100 (8.00%)

HPV, Human papillomavirus; IQR, Interquartile range; SD, Standard Deviation; ACE27, Adult Comorbidity Evaluation 27. Bold values p < 5% significance level.