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. 2018 Jul 23;8:273. doi: 10.3389/fonc.2018.00273

Table 2.

Comparison between HPV negative and HPV positive patients according to the TNM 7th edition. Classification of the HPV positive patients according to the TNM 8th edition.

T-stage (7th edition) HPV negative HPV positive p-value 0.127 T-stage (8th edition) HPV positive
T1 0/160 (0.00%) 12/100 (12.00%) T1 12/100 (12.00%)
T2 53/160 (33.13%) 41/100 (41.00%) T2 41/100 (41.00%)
T3 36/160 (22.50%) 19/100 (19.00%) T3 19/100 (19.00%)
T4a 42/160 (26.25%) 23/100 (23.00%) T4 28/100 (28.00%)
T4b 19/160 (11.88%) 5/100 (5.00%)
N-stage (7th edition) 0.018 N-stage (8th edition)
N0 37/160 (23.13%) 17/100 (17.00%) N0 17/100 (17.00%)
N1 28/160 (17.50%) 10/100 (10.00%) N1 57/100 (57.00%)
N2a 4/160 (2.50%) 5/100 (5.00%) N2 20/100 (20.00%)
N2b 43/160 (26.88%) 42/100 (42.00%) N3 6/100 (6.00%)
N2c 45/160 (28.13%) 20/100 (20.00%)
N3 3/160 (1.88%) 6/100 (6.00%)
Stage (7th edition) 0.504 Stage (8th edition)
I 1/160 (0.63%) 0/100 (0.00%) I 43/100 (43.00%)
II 19/160 (11.88%) 10/100 (10.00%) II 23/100 (23.00%)
III 26/160 (16.25%) 11/100 (11.00%) III 34/100 (34.00%)
IVa 92/160 (57.50%) 68/100 (68.00%) IV 0/100 (0.00%)
IVb 22/160 (13.75%) 11/100 (11.00%)

HPV: Human papillomavirus. Bold font: p < 5% significance levels.