Table 2.
Characteristics of dogs enrolled in a placebo-controlled study investigating the effects of CBD on osteoarthritis.
| Breed | Weight (kg) | Age (years) | Sex | Radiographic findings and OA localization | NSAID |
|---|---|---|---|---|---|
| Rottweiler | 35.3 | 10 | FS | - Moderate, intracapsular swelling with moderate osteophytosis, left stifle | Carprofen (2.1 mg/kg BID) |
| Mix | 30.6 | 13 | MC | - Moderate-to-severe, right-shoulder osteoarthrosis; mild, left-shoulder osteoarthrosis - Moderate-to-severe, bilateral hip osteoarthrosis |
None |
| Mix | 27.2 | 9 | FS | - Moderate medial coronoid remodeling (with fragmentation on the right) and bilateral elbow osteoarthrosis | None |
| Mix | 30.5 | 14 | MC | - Moderate enthesiopathies on right carpus; mild, left-antebrachiocarpal osteoarthrosis - Bilateral moderate coxofemoral osteoarthrosis |
None |
| Mix | 23.5 | 10 | FS | - Moderate bilateral stifle osteoarthrosis and moderate intracapsular swelling | Carprofen (2.2 mg/kg) |
| Mix | 28.1 | 10 | FS | - Moderate bilateral elbow osteoarthrosis - Moderate left-stifle osteoarthrosis with intracapsular swelling |
Metacam (0.1 mg/kg |
| English Bulldog | 25.2 | 8 | MC | - Severe osteoarthrosis, left elbow - Moderate intracapsular swelling and mild osteoarthrosis, right stifle |
Carprofen (2 mg/kg BID) |
| German Shorthaired Pointer | 21.5 | 14 | FS | - Moderate bilateral elbow osteoarthrosis | Carprofen (2.4 mg/kg BID) |
| Labrador Retriever | 26.1 | 13 | FS | - Bilateral severe stifle osteoarthrosis due to cranial cruciate ligament disease | Meloxicam (0.1 mg/kg SID) |
| Mix | 18.2 | 13 | FS | - Bilateral moderate elbow osteoarthrosis and medial epicondylitis | Meloxicam (0.1 mg/kg SID) |
| Mix | 22 | 9 | FS | - Moderate, stifle osteoarthrosis with moderate intracapsular swelling | None |
| Bernese Mountain Dog | 50 | 3 | M | - Bilateral severe elbow osteoarthritis, medial coronoid disease, and medial epicondylitis | Carprofen (2 mg/kg SID) |
| Belgian Malinois | 25.1 | 9 | FS | - Severe bilateral elbow osteoarthrosis - Bilateral moderate hip osteoarthrosis |
Carprofen (2 mg/kg BID) |
| Mix | 28.6 | 13 | FS | - Severe bilateral elbow osteoarthritis - Severe bilateral hip osteoarthritis |
None |
| Border Collie | 22 | 14 | MC | - Severe thoracolumbosacral osteophytosis - Multifocal carpal enthesiophytes |
None |
| Beagle | 17.6 | 5 | MC | - Mild left elbow osteoarthrosis, with possible medial coronoid disease - Moderate-to-severe bilateral stifle osteoarthrosis |
None |
FS, female spayed; MC, male castrated; Mix, mixed breed; SID, once daily; BID, twice daily.