Table 3.

Canine Brief Pain Inventory (Pain and Activity questions) and Hudson Scale mean and standard deviation; lameness, weight-bearing and pain scores median and ranges at each time for cannabidiol (CBD) and placebo oils.

	CBD oil			Placebo oil
	Week 0	Week 2	Week 4	Week 0	Week 2	Week 4
CBPI Pain (0–40)	21 ± 8	14 ± 6*	14 ± 8*	17 ± 7	19 ± 9	19 ± 9
CBPI activity interference (0–60)	35 ± 15	25 ± 15*	26 ± 14*	27 ± 15	29 ± 15	31 ± 16
Hudson (0–110)	54 ± 13	67 ± 15*	67 ± 10*	65 ± 14	64 ± 16	60 ± 19
Veterinary lameness§	3 (1–4)	3 (1–4)	3 (1–4)	3 (2–4)	3 (2–4)	3 (1–4)
Veterinary pain ∫	3 (3–4)	3 (2–4)*	3 (1–4)*	3 (2–4)**	3 (2–4)	3 (2–4)**
Veterinary weight-bearing =	2 (1–3)	2 (1–3)	2 (1–3)	2 (1–3)	2 (1–3)	2 (1–3)

^*Represents significant difference (p < 0.05) from baseline week 0 of CBD treatment.

^**Represents significant differences (p < 0.05) from week 2 of CBD oil treatment. §Lameness was scored as follows: 1 = no lameness observed/walks normally, 2 = slightly lame when walking, 3 = moderately lame when walking, 4 = severely lame when walking, 5 = reluctant to rise and will not walk more than 5 paces. ∫Pain on palpation was scored as follows: 1 = none, 2 = mild signs, dog turns head in recognition, 3 = moderate signs, dog pulls limb away, 4 = severe signs, dog vocalizes or becomes aggressive, 5 = dog will not allow palpation. = Weight-bearing was scored as follows: 1 = equal on all limbs standing and walking, 2 = normal standing, favors affected limb when walking, 3 = partial weight-bearing standing and walking, 4 = partial weight-bearing standing, non-weight-bearing walking, 5 = non-weight-bearing standing and walking.