Table 4.
Serum chemistry values of dogs receiving CBD or placebo oils.
| Reference | CBD oil | Placebo oil | |||||
|---|---|---|---|---|---|---|---|
| Week 0 | Week 2 | Week 4 | Week 0 | Week 2 | Week 4 | ||
| Sodium | 145–153 mEq/L | 149 ± 3 | 149 ± 2 | 149 ± 1 | 149 ± 1 | 149 ± 2 | 149 ± 2 |
| Potassium | 4.1–5.6 mEq/L | 4.9 ± 0.3 | 4.9 ± 0.5 | 4.9 ± 0.3 | 4.8 ± 0.4 | 4.9 ± 0.4 | 4.9 ± 0.3 |
| Chloride | 105–116 mEq/L | 110 ± 3 | 109 ± 3 | 109 ± 2 | 110 ± 2 | 110 ± 2 | 110 ± 2 |
| SUN | 10–32 mg/dL | 20 ± 9 | 20 ± 7 | 20 ± 6 | 19 ± 6 | 21 ± 7 | 19 ± 6 |
| Creatinine | 0.6–1.4 mg/dL | 1.0 ± 0.3 | 1.1 ± 0.3* | 1.0 ± 0.3* | 0.9 ± 0.3 | 1.0 ± 0.3* | 1.0 ± 0.3* |
| Calcium | 9.3–11.4 mg/dL | 10.4 ± 0.5 | 10.4 ± 0.4 | 10.3 ± 0.4 | 10.4 ± 0.6 | 10.4 ± 0.4 | 10.4 ± 0.4 |
| Phosphorus | 2.9–5.2 mg/dL | 3.8 ± 0.8 | 3.9 ± 0.8 | 3.9 ± 0.6 | 4.0 ± 0.7 | 3.9 ± 0.6 | 4.0 ± 0.5 |
| Magnesium | 1.4–2.2 mg/dL | 1.8 ± 0.2 | 1.8 ± 0.2 | 1.8 ± 0.2 | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 |
| Glucose | 63–118 mg/dL | 92 ± 9 | 89 ± 9 | 92 ± 9 | 97 ± 10* | 93 ± 8 | 97 ± 10* |
| ALT | 20–98 U/L | 93 ± 86 | 93 ± 88 | 114 ± 119 | 90 ± 89 | 222 ± 606 | 166 ± 284 |
| AST | 14–51 U/L | 31 ± 8 | 33 ± 13 | 34 ± 16 | 30 ± 8 | 56 ± 99 | 45 ± 34 |
| ALP | 17–111 U/L | 160 ± 212 | 238 ± 268 | 323 ± 407* | 204 ± 287 | 186 ± 287 | 175 ± 248 |
| GGT | 0–6 U/L | 4 ± 3 | 3 ± 2 | 3 ± 2 | 3 ± 2 | 4 ± 6 | 5 ± 4 |
| Bilirubin | 0.0–0.2 mg/dL | 0.1 ± 0.1 | 0.0 ± 0.1 | 0.1 ± 0.1 | 0.0 ± 0.1 | 0.0 ± 0.1 | 0.0 ± 0.1 |
| Total protein | 5.3–7.0 g/dL | 6.3 ± 0.4 | 6.4 ± 0.5 | 6.3 ± 0.4 | 6.3 ± 0.4 | 6.3 ± 0.4 | 6.3 ± 0.4 |
| Albumin | 3.1–4.2 g/dL | 3.7 ± 0.2 | 3.7 ± 0.2 | 3.7 ± 0.2 | 3.7 ± 0.2 | 3.7 ± 0.2 | 3.7 ± 0.2 |
| Globulin | 1.9–3.6 g/dL | 2.6 ± 0.3 | 2.6 ± 0.4 | 2.6 ± 0.4 | 2.6 ± 0.4 | 2.6 ± 0.4 | 2.6 ± 0.4 |
| Cholesterol | 138–332 mg/dL | 291 ± 64 | 301 ± 62 | 302 ± 62 | 295 ± 71 | 300 ± 71 | 308 ± 83 |
| CK | 48–260 U/L | 148 ± 81 | 147 ± 59 | 134 ± 61 | 139 ± 57 | 158 ± 80 | 168 ± 105 |
Data presented at mean + standard deviations. Asterisk
(*)
indicates significantly different (p < 0.05) serum concentration from baseline week 0 CBD treatment. SUN, serum urea nitrogen; ALT, alanine animotranferase; AST, aspartate animotransferase; ALP, alkaline phosphatase; GGT, gamma glutamyl transferase; CK, creatine kinase.