Table 4.

Deaths reported in study participants and related information during the rare disease study

Age at death (years)	Group	Molecular class	Gender	Autopsy performed	Manner of death—description	Cause of death
51.72	PWS	Uniparental disomy	Female	Unknown		Natural causes
32.44	PWS	Uniparental disomy	Male	Unknown		Natural causes
32.60	PWS	Deletion	Male	Unknown		Natural causes
1.93	PWS	Uniparental disomy	Female	Unknown	Pneumonia and septicemia	Pneumonia and septicemia
50.79	PWS	Uniparental disomy	Female	No	Gastric necrosis	Gastric necrosis
44.43	PWS	Imprinting defect	Female	Yes	Died in sleep, autopsy results pending	Unknown
14.79	EMO		Female	No	Diabetic ketoacidosis and resultant brain herniation	Brain herniation