FIGURE 7.

Protective potential of compounds isolated from Dioscorea villosa on depletion in glutathione level. HepG2 cells were exposed to 50 μM of non-cytotoxic compounds for 24 h prior to the addition of H₂O₂ for 24 h. All values are represented as mean ± SD. (i) Control; (ii) H₂O₂ (0.25 mM); (iii) Huangjiangsu A (50 μM) + H₂O₂ (0.25 mM); (iv) Pseudoprotodioscin (50 μM) + H₂O₂ (0.25 mM); (v) Methyl protobioside (50 μM) + H₂O₂ (0.25 mM); (vi) Protodioscin (50 μM) + H₂O₂ (0.25 mM); and (vii) Protodeltonin (50 μM) + H₂O₂ (0.25 mM). #p < 0.01 versus control, ^∗p < 0.05 and ^∗∗p < 0.01 versus H₂O₂ exposure.