Table 2.
Kinetics and compartmental analysis parameters in subjects with age under 30 years (young group) and with more than 60 years (older group).
| Young (n=20) |
Older (n=23) |
P | |
|---|---|---|---|
| k2,1 = k6,5 | 0.134±9.38x10-4 | 0.145±6.45x10-4 | <0.0001 |
| k3,1 = k7,5 | 0.150±2,93x10-4 | 0.129±5.88x10-4 | <0.0001 |
| k3,2 | 0.0216±0.0097 | 0.0155±7.07x10-3 | 0.0222 |
| k4,3 | 0.00122±0.00042 | 0.00470±0.00385 | 0.0071 |
| k3,4 | 2.72x10-6±0.00996 | 0.0321±0.0079 | <0.0001 |
| k0,4 | 3.74x10-7±0.00448 | 0.00309±0.00369 | 0.0173 |
| k7,6 | 0.0560±0.0007 | 0.0498±0.0005 | <0.0001 |
| k7,8 | 0.0578±0.0045 | 0.0422±0.0038 | <0.0001 |
| k8,7 | 0.00937±0.00561 | 0.00939±0.00471 | 0.9899 |
| k0,8 | 4.21x10-7±0.00433 | 0.0160±0.0025 | <0.0001 |
| 14C-CE FCR (min-1) | 0.019±0.010 | 0.008±0.007 | 0.0001 |
| 3H-TG FCR (min-1) | 0.027±0.014 | 0.030±0.017 | 0.5350 |
Data expressed in mean ± SD. ki,j in min-1, compartmental parameters as indicated in Fig 1. Fractional clearance rates of the emulsion cholesteryl esters (14C-CE FCR) and triglycerides (3H-TG FCR).