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. 2018 Aug 1;9(4):590–604. doi: 10.14336/AD.2017.0831

Figure 7. Effects of fucoidan on rotenone-induced reduction of mitochondrial complex activity in the rat ventral midbrain.

Figure 7

(A) Profiles of OCRs in the digitonin-permeabilized ventral midbrain tissue subjected to rotenone (red line) or fucoidan with rotenone (green line). (B-D) Quantification of basal respiration (B), complex I activity (C), and complex II activity (D) in the ventral midbrain of rats. Data are shown as means ± SEM (n = 3-4 per group). *P < 0.05 and **P < 0.01 versus vehicle group. #P < 0.05 and ##P < 0.01 versus model group (rotenone only). Abbreviation: P + M = pyruvate + malate, G = glutamate, S = succinate.