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. 2018 Jul 30;8:11384. doi: 10.1038/s41598-018-29885-7

Figure 2.

Figure 2

TSPO ligand-induced ATP release. ATP release from human red blood cells was measured using on line (20 °C, 0.75% Haematocrit, black bars) or off line (37 °C, 10% Haematocrit, grey bars) setups as described in material and methods. Values are the ratio between extracellular ATP (ATPe) levels after and before the addition of PK11195 (30 µM), Ro5-4864 (30 µM), NCS1018 (30 µM), TRO196221018 or 3 V (10 µM isoproterenol, 30 µM forskolin, 100 µM papaverin). Results are expressed as means ± SEM and considered different from basal (vehicle, unstimulated) values when **p < 0.01; ***p < 0.001; ****p < 0.0001, n = 6.