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Values for the relative IC50 of HCT116 and HCT116 DOXR after 24 h exposure to DOX, TS265 and their individual combination with tariquidar (inhibitor).
| Cell Culture | DOX | TS265 | DOX + Inhibitor | TS265 + Inhibitor |
|---|---|---|---|---|
| HCT116 | 0.38 ± 0.04 | 0.13 ± 0.01 | 0.38 ± 0.03 | 0.12 ± 0.01 |
| HCT116 DOXR | >6 | 0.14 ± 0.02 | 0.81 ± 0.06 | 0.15 ± 0.04 |
Concentrations are expressed in μM.
