Table I.

Primers used for the polymerase chain reaction.

Target gene	Sequence
MMP-9	F: 5′-CAAGCTGGACTCGGTCTTTGA-3′
	R: 5′-TTCAACTCACTCCGGGAACTCA-3′
PTX-3	F: 5′-CATCCAGTGAGACCAATGAGG-3′
	R: 5′-GTAGCCGCCAGTTCACCATTT-3′
VEGF-α	F: 5′-CCACTGAGGAGTCCAACATCA-3′
	R: 5′-CATTTACACGTCTGCGGATCTT-3′
PlGF	F: 5′-ACTCAGCTCTTCTCCTCCTGTG-3′
	R: 5′-ACGGTAATAAATACACGAGCCG-3′
HIF-1α	F: 5′-AACCACCTATGACCTGCTTGGT-3′
	R: 5′-TTGAGCGGCCTAAAAGTTCTTC-3′
VHL	F: 5′-TACCGAGGTCACCTTTGGC-3′
	R: 5′-GGAGGCATCGCTCTTTCAG-3′
GAPDH	F: 5′-TCATGACCACAGTCCATGCC-3′
	R: 5′-TCCACCACCCTGTTGCTGTA-3′

F, forward; R, reverse; MMP, matrix metalloprotein; PTX-3, pentraxin-related protein 3; VEGF, vascular endothelial growth factor; PlGF, placental growth factor; HIF, hypoxia-induciblefactor; VHL, von Hippell-Lindau protein.