Table 1.
Feature | Parameter | Number | Percentage |
---|---|---|---|
Cohort | Patient | 50 | 100 |
Age (years) | Mean ± s.d. | 46.5 ± 20.9 | n/a |
Median | 40 | n/a | |
Range | [10–96] | n/a | |
Interquartile range | 38.5 | n/a | |
Gender | Female | 20 | 40 |
Male | 30 | 60 | |
HBsAg | Negative | 23 | 46 |
Positive | 26 | 52 | |
Anti-HCV | Negative | 49 | 98 |
Positive | 1 | 2 | |
Tumor size (cm) | Mean ± s.d. | 13.9 ± 6.2 | n/a |
Median | 14 | n/a | |
Range | [2.5–29] | n/a | |
Interquartile range | 7.6 | n/a | |
Less than 5 cm | 3 | 6 | |
Between 5 and 10 cm | 12 | 24 | |
More than 10 cm | 35 | 70 | |
Tumor nodule | Single | 46 | 92 |
Multinodular | 4 | 8 | |
Vascular invasion | Absent | 38 | 76 |
Macro | 4 | 8 | |
Micro | 3 | 6 | |
Macro and micro | 5 | 10 | |
Tumor grade | G1 | 14 | 28 |
G2 | 24 | 48 | |
G3 | 12 | 24 | |
Tumor growth pattern | Acinar | 2 | 4 |
Compact | 2 | 4 | |
Mixed growth pattern | 19 | 38 | |
Trabecular | 27 | 54 | |
AFP (ng/mL) | Mean ± s.d. | 76,255.9 ± 140,085.6 | n/a |
Median | 5,286.5 | n/a | |
Range | [1–481,050] | n/a | |
Interquartile range | 72,455.7 | n/a |
Percentages are expressed as a ratio of the 50 patients investigated for the considered parameter. Tumor architecture and grading (G1–G4) were defined according to established classifications50,51. Mean values are presented with ±standard deviation (s.d.). AFP, alpha-fetoprotein; HBsAg, HBV surface antigen; HCV, hepatitis C virus; n/a, not applicable.