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. 2018 Jul 6;53(3):949–960. doi: 10.3892/ijo.2018.4473

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Copyright: © Jia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of combination therapy on T-lymphocyte infiltration into tumour tissues. Tumour tissue samples were harvested on day 21 after tumour inoculation. (A) Infiltration of CD4⁺ and CD8⁺ T cells in tumour tissues was determined by immunohistochemical analyses (each group contained three independent samples). (B) Protein expression levels of CD4 and CD8 in tumour tissues were analysed using western blotting. (C) Semi-quantitative results of CD4 and CD8 protein levels. n=9/group. ^**P<0.01. CD, cluster of differentiation; L-MT, L-methyl-tryptophan.