Table 3.

Comparison of baseline characteristics in the higher- and lower-response subpopulations

Baseline characteristics	Higher-response subpopulation (n=51)	Lower-response subpopulation (n=35)	P-value
Demographics
Age (years), mean (SD)	52.0 (14.1)	47.8 (14.0)	0.27
Male, n (%)	26 (51.0)	14 (40.0)	0.32
White, n (%)	48 (94.1)	35 (100.0)	0.27
Disease characteristics
Cause of major intestinal resection, n (%)
Crohn’s disease	16 (31.4)	2 (5.7)	<0.01*
Vascular disease	10 (19.6)	19 (54.3)	<0.01*
Injury	4 (7.8)	4 (11.4)	0.71
Volvulus	7 (13.7)	2 (5.7)	0.30
Cancer	3 (5.9)	0 (0.0)	0.27
Other	11 (21.6)	8 (22.9)	0.89
Colon in continuity, n (%)	18 (35.3)	31 (88.6)	<0.01*
Percentage of colon remaining, mean (SD)	18.5 (26.3)	65.0 (31.3)	<0.01*
Estimated remaining small intestine length (cm), mean (SD)	87.0 (70.6)	61.6 (51.7)	0.07
Estimated remaining small intestine length (cm), n (%)			0.11
<60	20 (42.6)	20 (60.6)
≥60	27 (57.4)	13 (39.4)
Presence of distal/terminal ileum, n (%)	9 (17.6)	15 (42.9)	0.01*
Presence of ileocecal valve, n (%)	2 (3.9)	11 (31.4)	<0.01*
Presence of stoma, n (%)	33 (64.7)	5 (14.3)	<0.01*
Time since last small bowel resection (years), mean (SD)	6.6 (6.1)	8.2 (8.6)	0.88
Baseline PS characteristics
Baseline PS volume at randomization, n (%)			<0.01*
≤6 L/week	1 (2.0)	14 (40.0)
>6 L/week	50 (98.0)	21 (60.0)
Time since start of PS dependency (years), mean (SD)	6.7 (5.8)	5.8 (6.3)	0.20
Concomitant narcotics use, n (%)	16 (31.4)	11 (31.4)	1.00

Note:

^*P<0.05.

Abbreviation: PS, parenteral support.