Table 4.
Preterm birth | ||||||
SGA | Before 32 weeks | Before 37 weeks | ||||
Type of anti-hypertensive therapy | Rate (%)* | Adjusted OR (95% CI)** | Rate (%) | Adjusted OR (95% CI) | Rate (%) | Adjusted OR (95% CI) |
None | 9.0 | 1.0 | 1.9 | 1.0 | 12.2 | 1.0 |
β-blocker | 19.9 | 2.3 (1.6–3.3) | 14.7 | 7.6 (4.1–14.1) | 45.3 | 5.1 (3.8–6.9) |
Non-β-blocker | 20.7 | 2.1 (1.3–3.4) | 20.7 | 13.4 (6.8–26.2) | 62.2 | 10.3 (7.0–15.3) |
Both β-blocker and non-β-blocker | 28.5 | 2.7 (1.8–3.9) | 34.7 | 21.1 (11.6–38.3) | 87.5 | 41.2 (27.7–61.2) |
*Represents the rate for each perinatal outcome according to type of antihypertensive therapy **All odds ratios were adjusted for maternal age, parity, pre-pregnancy weight, history of delivery before 34 weeks, history of hypertension in a previous pregnancy, cigarette smoking, pre-pregnancy diabetes mellitus, pre-pregnancy renal dysfunction, use of prednisone, and gestational age at which blood pressure first increased above 140/90 mm Hg.