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. Author manuscript; available in PMC: 2019 Jan 17.
Published in final edited form as: Sci Signal. 2018 Jul 17;11(539):eaao3964. doi: 10.1126/scisignal.aao3964

Fig. 5. Schematic demonstrating the unique and redundant functional domains of the IAP proteins.

Fig. 5

(A) Swapping XIAP’s BIR2 domain into cIAP1 or cIAP2 results in no conversion of protein function. (B) Interchange of the RING domains of cIAP1 and cIAP2 with XIAP results in proteins with equivalent function.