Table 1.
NADH oxidation in M. smegmatis membranes with complemented Mtb ndh or ndhA is inhibited by the TQZ and THI scaffolds.
| Compound |
Mtb Ndh IC50 (nm) |
Msmeg Ndh IC50 (nm) |
Mtb NdhA IC50 (nm) |
|---|---|---|---|
| TQZ | 64.7 | 10.7 | 42.5 |
| THI | 25.0 | 44.3 | 15300 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.