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. 2018 Jul 30;13(7):e0200773. doi: 10.1371/journal.pone.0200773

Fig 3. Phylogeny for sequences obtained in typing studies.

Fig 3

Maximum likelihood tree produced in MEGA 6 for the 83 bp overlapping fragment of the TP0548 gene typed with MLST, ECDCT and SBMT. The letters A-S stand for the classification in ECDCT and SBMT typing studies. Rabbit passed strains BAL9 was included as representative for type “H”, which was not found among clinical samples yet. For subtype”L” the number of identified samples is not known [37]. Subtype”J” does not correspond to TPA but was found in T. pallidum subsp. endemicum and T. pallidum subsp. pertenue [35, 38]. As observed, TP0548 does not distinguish TPA from TEN or TPE, reflecting potential recombination events between these three. All samples were obtained directly from patients except the BAL9 (passed through rabbits) and isolates from Tanzania (isolated from flies). The numbers in the brackets represent the number of samples identified in the given country. The numbers in red represent the Swiss and French samples from this study.