Table 3. Cases, incidence, mortality and demographics of sepsis patients ≥18y in Germany 2007–2013 by different ICD code abstraction strategies.
| Characteristic | ICD abstraction strategies for sepsis (incl. severe sepsis) |
ICD abstraction strategies for severe sepsis* | |||
|---|---|---|---|---|---|
| R codes (R65.0!, R65.1!, R57.2) | explicit sepsis coding* | R codes (R65.1!, R57.2) | explicit sepsis coding +odf** | implicit sepsis coding (inf+odf**) | |
| cases 2007–2013 | 1,098,222 | 1,511,510 | 580,778 | 941,957 | 4,785,511 |
| incidence / 100,000 population ≥18y / year | 231 | 318 | 122 | 198 | 1006 |
| hospital deaths / 100,000 population ≥18y / year | 71 | 87 | 57 | 77 | 200 |
| age (y, median [IQR]) | 72 [62–80] | 72 [61–80] | 72 [62–80] | 72 [62–80] | 75 [65–82] |
| male sex (%) | 56 | 55 | 58 | 57 | 52 |
| mortality (%) | 30.8 | 27.5 | 47.0 | 38.7 | 19.8 |
| ICU treatment (%) | 37.4 | 31.8 | 53 | 45.2 | 25.0 |
| CCI (median [IQR] | 3 [1–4] | 2 [1–4] | 3 [1–5] | 3 [1–5] | 3 [1–4] |
| hospital LOS (d, median [IQR]) | 15 [8–28] | 14 [8–27] | 17 [8–33] | 17 [8–32] | 13 [7–22] |
* explicit sepsis codes: A02.1, A20.0, A20.7, A21.7, A22.7, A24.1, A26.7, A28.2, A32.7, A39.2, A39.3, A39.4, A39.1, A40.-, A41.-, A42.7, A48.3, B00.7, A54.8, B37.7, B37.6, B49, A49.9, R65.0!, R65.1!, R57.2
** organ dysfunction
CCI = Charlson Comorbidity Index, IQR = interquartile range