Table 3. Ca²⁺ dynamics parameters.

Parameter	Symbol	Value	Reference
Diffusion Coefficient of Ca2+	DCa	0.6 μm2/ms	[97]
Resting Intracellular Ca2+ Concentration	[Ca]i	1.36*10−4 mM	[44]
Resting ER Ca2+ Concentration	[Ca]ER	0.4 mM	[71, 98]
Resting Mitochondrial Ca2+ Concentration	[Ca]MT	2*10−4 mM	[99, 100]
Intracellular Ca2+ Buffer Binding Ratio	β	370	[95]
Resting Intracellular IP3 concentration	[IP3]0	1.60*10−4 mM	[98]
PMCA Parameters
Pump Rate	K1	3.74*107 /mM-s	Tuned
Pump Rate	K2	2.5*105 /s	Tuned
Pump Rate	K3	500 /s	Tuned
Pump Rate	K4	5 /mM-s	Tuned
Initial Free Pump density	pump0	4.232*10−13 mol/cm2	Tuned