Table 1.
The clinical profile of the eight study subjects containing a PTAP motif duplication
M indicates the month of sample collection at a 6-month interval from baseline M0. - indicates information is not available. PVL indicates plasma viral load (number of RNA copies/ml).
| Subject ID | Age/gender | Enrollment date | PVL |
CD4 (cells/μl) |
HLA profile |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M0 | M6 | M12 | M0 | M6 | M12 | M18 | M24 | HLA-A | HLA-B | HLA-C | ||||||
| T004 | 29/Female | 12/16/2010 | 33,784 | 36,627 | 112,577 | 553 | 442 | 508 | 359 | 321 | 0201 | 2402 | 5101 | 4006 | 0602 | 1503 |
| 2012 | 28/Female | 1/20/2011 | 6,070 | - | - | 1,087 | 1,214 | 946 | - | 1,187 | 2402 | 2402 | 4402 | 4402 | 0701 | 0701 |
| 2018 | 35/Female | 1/24/2011 | 6,493 | - | - | 825 | 884 | - | - | - | 2402 | 2402 | 1341 | 4006 | 0602 | 1502 |
| 2020 | 38/Male | 2/25/2011 | 70,025 | - | - | 570 | 475 | 484 | - | 422 | 0101 | 0211 | 3501 | 5701 | 0602 | 1510 |
| 2032 | 45/Male | 8/9/2011 | 9,468 | - | - | 671 | 664 | 699 | 539 | 542 | 0101 | 02 | 0705 | 5701 | 0602 | 0701 |
| 2037 | 29/Male | 8/9/2011 | 1,505 | - | - | 732 | 612 | 554 | 470 | 549 | 1101 | 3301 | 5201 | 5201 | 1202 | 1202 |
| T014a | 35/Female | 2/25/2011 | 2,888 | 4,578 | - | 553 | 484 | 376 | 436 | 425 | 1101 | 3301 | 2701 | 5801 | 0202 | 0302 |
| 2006b | 46/Female | 9/26/2011 | 662 | - | - | 659 | - | - | 580 | 563 | 0101 | 2402 | 3901 | 5701 | - | - |
a In subject T014, PTAP duplication was found only at M24, not used in the subsequent analyses.
b Sample from subject 2006 was available only at baseline.