Figure 1.
Binding of norovirus GII.4 (Sydney, 2012, JX459908) VLPs on neoglycolipid arrays derived from high-mass human milk oligosaccharides. A, neoglycolipid fractions 1–42 correspond to HMO fractions listed in Table S1. Two micrograms of neoglycolipid were immobilized per well in a duplicate assay on polystyrene plates. B, neoglycolipids derived from standard HMOs (LNFP-I, lacto-N-fucopentaose-I; LNneoFP-I, lacto-N-neofucopentaose-I; LNFP-II, lacto-N-fucopentaose-II) and selected HMO fractions were tested in triplicate for comparative norovirus GII.4 VLP binding.
