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Cardiac phenotypic defects observed in Jarid2Nkx mice
Mice at various stages were examined by H&E staining on transverse sections.
| Stages | Genotype | No. of mice | VSD | Hypertrabeculation | Thin myocardium |
|---|---|---|---|---|---|
| E15.5–E19.5 | Control (+/+;f/f) | 10 | 0 | 0 | 0 |
| Jarid2Nkx (C/+;f/f) | 11 | 10 (91%) | 9 (82%) | 8 (73%) | |
| Nkx2.5-Cre (C/+;+/+) | 7 | 0 | 0 | 0 | |
| Heterozygous (C/+;f/+) | 7 | 1 (14%) | 1 (14%) | 1 (14%) |
