Table 4.
Phthalate metabolite | Unadjusted | Adjusteda | ||||
---|---|---|---|---|---|---|
HRb | 95% CI | p-Value | HR | 95% CI | p-Value | |
MEP | 1.04 | 0.93, 1.15 | 0.47 | 1.04 | 0.94, 1.16 | 0.42 |
MBP | 1.00 | 0.89, 1.12 | 0.96 | 1.03 | 0.92, 1.15 | 0.60 |
MiBP | 1.16 | 1.01, 1.33* | 0.03 | 1.16 | 1.01, 1.34* | 0.03 |
MECPP | 0.97 | 0.84, 1.12 | 0.73 | 0.98 | 0.84, 1.13 | 0.77 |
MEHHP | 0.99 | 0.86, 1.13 | 0.90 | 0.99 | 0.88, 1.14 | 0.93 |
MEOHP | 1.01 | 0.88, 1.15 | 0.91 | 1.01 | 0.88, 1.16 | 0.86 |
MEHP | 0.96 | 0.86, 1.07 | 0.50 | 0.96 | 0.85, 1.08 | 0.47 |
MBzP | 0.99 | 0.88, 1.12 | 0.99 | 1.02 | 0.90, 1.15 | 0.69 |
MCOP | 1.04 | 0.91, 1.19 | 0.48 | 1.09 | 0.95, 1.25† | 0.05 |
MCPP | 1.02 | 0.88, 1.17 | 0.81 | 1.05 | 0.91, 1.22 | 0.50 |
MCNP | 1.02 | 0.90, 1.14 | 0.74 | 1.03 | 0.92, 1.17 | 0.56 |
0.99 | 0.96, 1.03 | 0.77 | 0.98 | 0.94, 1.03 | 0.57 |
Note: CI, confidence interval; DEHP, di(2-ethylhexyl) phthalate; HR, hazard ratio; MBP, mono-n-butyl phthalate; MBzP, monobenzyl phthalate; MCNP, monocarboxy-isononyl phthalate; MCOP, monocarboxy-isooctyl phthalate; MCPP, mono(3-carboxypropyl) phthalate; MECPP, mono(2-ethyl-5-carboxypentyl) phthalate; MEHHP, mono(2-ethyl-5-hydroxyhexyl) phthalate; MEHP, mono(2-ethylhexyl) phthalate; MEOHP, mono(2-ethyl-5-oxohexyl) phthalate; MEP, monoethyl phthalate; MiBP, mono-isobutyl phthalate.
,
.
HR adjusted for parental asthma/rhinitis/eczema, maternal smoking, maternal age, maternal BMI, maternal education level, gestational age, number of siblings, and recruitment center.
HR according to the proportional Cox’s model.